Cheezer's is a restaurant that sells grilled cheese sandwiches and variants of it, as seen in "Grilled Cheese Deluxe". They're extremely busy, and seem to cater heavily toward astronauts. A Grilled Cheese Deluxe costs $2.50. Cheezer's also appeared briefly in the episode "Cool Bikes", when Mordecai and Rigby drove there in The Muskrat 5000 during the introductory montage. Cheezer's was also seen in "Trash Boat" when Rigby wanted to work there. Also, in the episode "Out of Commission", When Mordecai and Rigby and Cart go to Cheezers, they go inside and cart broke the door entrance.
- In Grilled Cheese Deluxe, the sign for Cheezer's is red, but in the other two episodes it is seen in, the sign is purple.
- Cheezer's is a combination of both Subway and McDonald's but Cheezers' is actually a heavy parody of Cheeseboy.
Cheezer's might be a reference to the 90's alternative band Weezer.