|Voiced by:||Natasha Leggero|
|Appears in:||"Access Denied"|
Ladonna is an antagonist appearing in "Access Denied". She first appears walking into The Box with a fancy outfit and is the owner of the club. When she became angry at Mordecai for speaking out, she let out a vicious energy from her body.
She wears a black gown with neon yellow stripes. She also has blonde-styled hair, golden rings like bracelets, and black high heels.
- She is most likely a crossover of "Madonna" and "Lady Gaga" as her name implies, plus having a resemblance to both pop idols.
- Her name literally means "the woman" in Italian.
"Well, I am the owner of this stuck-up club, and I want you two gone."